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Oleic acid CAS#112-80-1
Oleic acid CAS#112-80-1
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Oleic acid CAS#112-80-1
Chemical Name:Oleic acid
CAS :112-80-1
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Application:
Oleic acid is used as an emulsifying agent in foods and topical pharmaceutical formulations. It has also been used as a penetration enhancer in transdermal formulations,to improve the bioavailability of poorly water-soluble drugs in tablet formulations, and as part of a vehicle in soft gelatin capsules, in topical microemulsion formulations,in oral self-emulsifying drug delivery systems,in oral mucoadhesive patches,and in a metered dose inhaler.Oleic acid was shown to be an important factor in the hypoglycemic effect produced by multiple emulsions containing insulin intended for intestinal delivery of insulin.
The phase behavior of sonicated dispersions of oleic acid has been described,and mechanisms for the topical penetrationenhancing actions of oleic acid have been presented.
Oleic acid has been reported to act as an ileal ‘brake’ that slows down the transit of luminal contents through the distal portion of the small bowel.
Oleic acid labeled with 131I and 3H is used in medical imaging.
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